Platform Technology

DELAYS IN PROGRESSING A BIOPHARMACEUTICAL TO MARKET WILL COST $1MM/DAY1
REGARDLESS OF WHETHER THOSE DELAYS OCCURRED IN DISCOVERY OR DEVELOPMENT…
EVERY DAY COUNTS!

 

PF Technology Diagram

Let Combinatorial Biology Provide the Solution

The Pfēnex Expression TechnologyTM platform is a microbial, Pseudomonas fluorescens-based platform technology that has repeatedly demonstrated its ability to rapidly produce difficult to express proteins by introducing the concept of parallel processing to expression strain development. Pfenex has replaced the traditional, linear and iterative approach to strain development with a high-throughput, parallel processing model that allows construction and testing of 1,000s of unique expression strains combining novel gene expression strategies and host cell phenotypes within five weeks. This has allowed Pfenex to rapidly identify production strains capable of expressing very complex proteins at high titers, sometimes with yields of more than 20 g/l and with very high quality profiles.

 

 

 

1 (US) (Maloff, 1999).