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The Development Protein Challenge
Every drug developer seeks to rapidly identify a robust host strain early in the clinical development lifecycle that can be scaled throughout clinical development and commercialization to meet product demand. Identifying a host strain producing high titers of soluble, active protein is critical to minimizing long term cost of goods as well as avoiding potential regulatory delays due to poor protein quality or insufficient productivity of the selected host.
The Pfenex Development Protein Solution
Pfēnex Expression TechnologyTM leverages its broad toolbox and high throughput robotically-enabled strain screening platform to screen thousands of strains to rapidly identify the ideal production strain expressing the highest titers of soluble, active, high quality protein. Pfenex scientists routinely progress from target gene to an identified production strain and fermentation process within 8 weeks, enabling our partners’ clinical development programs to proceed and keeping CMC off of the critical path.